Skin Boosters · Apgujeong, Seoul

Salmon DNA Boosters

PDRN and PN injections from salmon DNA that help damaged, thinning skin regenerate and hold moisture.

Salmon DNA Boosters
Skin Boosters · Apgujeong, Seoul

Salmon DNA Boosters

PDRN and PN injections from salmon DNA that help damaged, thinning skin regenerate and hold moisture.

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Salmon DNA Boosters
Quick answer
Salmon DNA boosters are injectable skin treatments based on polydeoxyribonucleotide (PDRN) or polynucleotide (PN) fragments purified from salmon. They may support tissue repair, reduce inflammation and improve hydration and elasticity. At Oaro Dermatology Clinic in Apgujeong, Seoul, a board-certified dermatologist chooses between PDRN and PN formulations such as Rejuran and injects them into the dermis over a course of three sessions.

Every plan at Oaro Dermatology Clinic begins with a 1:1 skin diagnosis by a board-certified dermatologist, so the dose, device settings and session count are set for your skin rather than a template. Meet our doctors or ask about your own skin .

At a glance
Procedure time 40–60 minutes including numbing
Anaesthesia Topical numbing cream
Downtime Small bumps for 1–2 days (PN) or almost none (PDRN)
Sessions 3 sessions, 2–4 weeks apart
Results last 6–12 months
Performed by Board-certified dermatologist
Overview

What are salmon DNA boosters?

Salmon DNA boosters are a family of injectables whose active ingredient is DNA fragments extracted from salmon milt. Because salmon DNA is structurally very close to human DNA, it is well tolerated and has been used in Korean medicine for wound healing for years. There are two main forms. PDRN (polydeoxyribonucleotide) consists of shorter fragments and is used for anti-inflammatory and healing effects, often as a lighter booster or as part of a mesotherapy cocktail. PN (polynucleotide) consists of longer chains with a gel-like texture and is the ingredient in Rejuran Healer, which stays in the dermis longer and is used for elasticity and texture.

In Seoul, salmon DNA boosters are chosen for skin that looks tired rather than wrinkled: dehydration, dullness, post-acne redness, thinning under the eyes and the roughness that follows years of sun. They are also used as a recovery step after lasers and as a gentle option for sensitive skin that reacts to acids.

How salmon DNA boosters work at Oaro

At Oaro Dermatology Clinic in Apgujeong the choice between PDRN and PN is made by a board-certified dermatologist after examining the skin, not by package. Lighter PDRN sessions are often delivered by injector or layered after Aquapeel for hydration and calming, while PN is injected by hand in a fine grid where density and elasticity are the goal. Both are placed under topical numbing in a session of about 40–60 minutes. Treatment is repeated three times at two to four week intervals, then maintained every six to twelve months. You can compare these with the other options in our Skin Boosters range or ask about PDRN injections as a standalone treatment.

Salmon DNA Boosters

Why patients choose Oaro

  • Diagnosis and treatment by a board-certified dermatologist, not a technician
  • Genuine devices and products: Ultherapy, Thermage FLX, Helios Pico, Rejuran, Juvelook
  • One treatment plan, written down, with aftercare and follow-up
  • Private 1:1 rooms in Cheongdam Tower, 8 minutes from Apgujeong Rodeo Station
  • English-friendly coordination and clear, itemised pricing
Treatment goals

Common goals for salmon DNA boosters

Hydration that lasts

Patients with dry, dehydrated skin use PDRN or PN to improve moisture retention beyond what topical products achieve.

Calmer post-acne skin

The anti-inflammatory effect may reduce lingering redness and support healing of acne-damaged areas.

Elasticity in thin skin

Under-eye and neck skin that has lost spring often responds to PN placement.

Gentle recovery after lasers

A salmon DNA session after resurfacing may shorten downtime. Discuss timing on our booking page.

Treatment room at Oaro Dermatology Clinic, Apgujeong
Your visit

What to expect

1. Consultation & diagnosis

Your dermatologist examines hydration, texture and inflammation, checks for allergies to fish products, and recommends PDRN, PN or a sequence of both along with the number of sessions.

2. Injection session

After 20–30 minutes of numbing cream, the product is delivered either by a multi-needle injector for even superficial coverage or by hand for targeted zones such as the eye area. The injection stage takes 15–20 minutes and ends with a cooling mask.

3. Aftercare & follow-up

Written aftercare is provided. Any small bumps settle within a day or two. The doctor reviews your skin at each visit and may adjust between PDRN and PN as the response becomes clear.

Cost guide

Salmon DNA booster cost in Seoul

PDRN sessions are generally less expensive than PN, which uses more product per session. Typical 2026 ranges in Apgujeong clinics are listed below.

Option Typical range (KRW)
PDRN booster session (full face) 150,000–300,000
PN (Rejuran) 2cc session 250,000–450,000
PDRN under-eye or neck add-on 80,000–150,000
Course of 3 sessions 450,000–1,200,000

Exact pricing is confirmed at consultation after examination.

Aftercare

Aftercare

  • Avoid make-up for 12 hours and cleanse gently that evening.
  • Leave any small bumps alone; they resolve naturally within one to two days.
  • Skip saunas, hot baths and alcohol for 48 hours.
  • Apply sunscreen each morning and avoid strong sun for a week.
  • Pause retinoids and exfoliating acids for three days.
Dr. Chang-hyun Kim, board-certified dermatologist at Oaro Dermatology Clinic
Medically reviewed by

Dr. Chang-hyun Kim, M.D.

Board-certified dermatologist and Representative Director of Oaro Dermatology Clinic, Cheongdam. Ulthera Certified Treatment Provider, Thermage FLX Master Certified, and full member of the Korean Dermatological Association, the Korean Society for Dermatologic Laser and the Korean Filler Society.

FAQ

Frequently asked questions

What is the difference between PDRN and PN?

PDRN uses shorter DNA fragments and is lighter and calming; PN uses longer chains, stays in the skin longer and is the ingredient in Rejuran Healer. Your dermatologist chooses based on your goal.

Are salmon DNA boosters safe if I am allergic to fish?

The DNA is highly purified and reactions are rare, but you must tell your doctor about any fish allergy so the decision is made carefully.

How quickly will my skin improve?

Hydration and calmness often improve within one to two weeks; texture and elasticity change over the full course.

Can salmon DNA boosters replace fillers?

No. They improve skin quality but do not add volume. Volume loss is addressed with fillers or collagen stimulators.

How often should I repeat them?

After the initial three sessions, a maintenance session every six to twelve months is usual in Seoul.

Explore related care

Often considered together

Private 1:1 consultation

Plan your treatment with a board-certified dermatologist in Apgujeong

Tell us what you would like to change, and we will examine your skin, explain the options and give you a written plan with clear pricing. English-speaking coordinators are available for international patients.